Open AccessManagement of metabolic syndrome through probiotic and prebiotic interventions
Author(s) -
Rashmi Hogarehalli Mallappa,
Namita Rokana,
Raj Kumar Duary,
Harsh Panwar,
V. K. Batish,
Sunita Grover
Publication year - 2012
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.91178
Subject(s) - prebiotic , medicine , probiotic , metabolic syndrome , type 2 diabetes , obesity , psychological intervention , intensive care medicine , dietary management , management of obesity , gut flora , diabetes mellitus , bioinformatics , weight loss , endocrinology , food science , immunology , biology , psychiatry , genetics , bacteria
Metabolic syndrome is a complex disorder caused by a cluster of interrelated factors that increases the risk of cardiovascular diseases and type 2 diabetes. Obesity is the main precursor for metabolic syndrome that can be targeted in developing various therapies. With this view, several physical, psychological, pharmaceutical and dietary therapies have been proposed for the management of obesity. However, dietary strategies found more appropriate without any adverse health effects. Application of probiotics and prebiotics as biotherapeutics is the new emerging area in developing dietary strategies and many people are interested in learning the facts behind these health claims. Recent studies established the role of probiotics and prebiotics in weight management with possible mechanisms of improved microbial balance, decreased food intake, decreased abdominal adiposity and increased mucosal integrity with decreased inflammatory tone. Hence, the above "Pharmaco-nutritional" approach has been selected and extensively reviewed to gain thorough knowledge on putative mechanisms of probiotic and prebiotic action in order to develop dietary strategies for the management of metabolic syndrome.