Open AccessRenin-angiotensin system activity in vitamin D deficient, obese individuals with hypertension: An urban Indian study
Author(s) -
Sunil Kumar Kota,
Siva Krishna Kota,
Sruti Jammula,
Lalit Kumar Meher,
Sagar Suman Panda,
Prabhas Rranjan Tripathy,
Kirtikumar D Modi
Publication year - 2011
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.86985
Subject(s) - medicine , renin–angiotensin system , plasma renin activity , vitamin d and neurology , endocrinology , blood pressure
Elevated renin-angiotensin-aldosterone system (RAAS) activity is an important mechanism in the development of hypertension. Both obesity and 25-hydroxy vitamin D [25(OH)D] deficiency have been associated with hypertension and augmented renin-angiotensin system (RAS) activity. We tried to test the hypothesis that vitamin D deficiency and obesity are associated with increased RAS activity in Indian patients with hypertension.