Open AccessHypothalamic pituitary dysfunction in acute nonmycobacterial infections of central nervous system
Author(s) -
Dinesh Dhanwal,
Sanjay Kumar,
Annirudha Vyas,
Alpana Saxena
Publication year - 2011
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.84873
Subject(s) - medicine , meningitis , meningoencephalitis , viral meningitis , endocrine system , hormone , pediatrics , immunology , bacterial meningitis
Acute and chronic central nervous system (CNS) infections are not uncommon in tropical countries and are associated with high morbidity and mortality if specific targeted therapy is not instituted in time. Effects of tubercular meningitis, a form of chronic meningitis on hypothalamic pituitary axis, are well known both at the time of diagnosis and after few months to years of illness. However, there are few reports of pituitary dysfunction in subjects with acute CNS infections. Therefore, this study was aimed at evaluating the pituitary hormonal profile in patients with nonmycobacterial acute meningitis at the time of presentation.