Open AccessThe inositols and polycystic ovary syndrome
Author(s) -
Bharti Kalra,
Sanjay Kalra,
Jai Bhagwan Sharma
Publication year - 2016
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.189231
Subject(s) - polycystic ovary , medicine , inositol , endocrine system , randomized controlled trial , endocrinology , ovary , bioinformatics , gynecology , insulin resistance , diabetes mellitus , hormone , biology , receptor
This review describes the rationale, biochemical, and clinical data related to the use of inositols in polycystic ovary syndrome (PCOS). It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol (MDI), with randomized controlled trials conducted in women with PCOS, and utilizes these data to suggest pragmatic indications and methods for using MDI combination in PCOS. Rationally crafted inositol combinations have a potential role to play in maintaining metabolic, endocrine, and reproductive health in women with PCOS.