Open AccessChronic sub-clinical inflammation in the abdominal adipose tissue – Evaluation of inflammatory cytokines and their link with insulin resistance in metabolically obese South Indians: Across-sectional observational study
Author(s) -
Manjunath Premanath,
Basavanagowdappa Hathur,
Mahesh Mahadevaiah,
M Suresh Babu,
D Devananda
Publication year - 2016
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.172244
Subject(s) - medicine , proinflammatory cytokine , insulin resistance , adiponectin , body mass index , endocrinology , waist , abdominal obesity , homeostatic model assessment , adipose tissue , high density lipoprotein , lipid profile , obesity , inflammation , cholesterol
To measure the levels of proinflammatory cytokines tumor necrosis factor-alpha (TNF-α), interleukin-6(IL-6), and high-sensitive C-reactive protein (hs-CRP) and the anti-inflammatory cytokine adiponectin (AN) in obese South Indian subjects and to ascertain whether or not a causal role could be ascribed to these cytokines in the development of insulin resistance (IR).