Open AccessCentral pontinemyelinosis, hyperparathyroidism, hypokalemia
Author(s) -
Sanjeev Kishore,
D Kandasamy,
Viveka P Jyotsna
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.119523
Subject(s) - hypokalemia , medicine , hyponatremia , central pontine myelinolysis , polydipsia , hyperparathyroidism , nephrogenic diabetes insipidus , hypomagnesemia , gastroenterology , pediatrics , endocrinology , vasopressin , diabetes mellitus , magnesium , materials science , metallurgy
Central pontinemyelinolysis (CPM) is one of the rare non-inflammatory demyelinating diseases of the pons and very rarely it can involve extrapontine structure as well. The exact etiopathogenesis of this condition is still unclear. Rapid correction of hyponatremia has been attributed as a most common factor, but alcoholism, malnutrition, prolonged use of diuretics, psychogenic polydipsia, post liver transplant and hypokalemia have also been attributed as a causative factor. We describe a case of hyperparathyroidism with concomitant hypercalcemia accompanied by central pontine myelinosis without hyponatremia/hyperosmolality or associated rapid corrections of sodium, which developed as a consequence of severe hypokalaemia.