Open AccessLithium-induced parathyroid dysfunction: A new case
Author(s) -
C. P. P. Nair,
Riju Ramachandran,
Pradeep Jacob,
Merin Babu
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.117223
Subject(s) - medicine , hyperparathyroidism , parathyroidectomy , lithium (medication) , parathyroid gland , lithium carbonate , endocrinology , calcium , urology , parathyroid hormone , chemistry , ionic bonding , ion , organic chemistry
Lithium salts are widely used in psychiatric practice and are known to induce thyroid dysfunction. Lithium-induced parathyroid dysfunction is rare. We are reporting a case of hyperparathyroidism in a 28-year-old female patient who was on lithium carbonate for 2 years, when she developed osteopenia and girdle girdle-type muscle weakness. Biochemical parameters showed hyperparathyroidism with shift of calcium creatinine clearance ratio to 0.013, indicating an error in threshold of calcium sensing receptor. The patient eventually required parathyroidectomy and the histology of the gland showed atypical features.