Open AccessAcute mania after thyroxin supplementation in hypothyroid state
Author(s) -
Rohit Verma,
Ankur Sachdeva,
Yogendra Singh,
Yatan Pal Singh Balhara
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.117220
Subject(s) - mania , medicine , bipolar disorder , mood , endocrinology , depressive symptoms , pediatrics , psychiatry , diabetes mellitus
The current literature variedly ascribes depressive and manic symptoms to hypo- and hyperthyroid state, respectively, reporting mania in hypothyroidism as an unusual entity. More unusual is precipitation of manic state in hypothyroid subjects after thyroxine supplementation for which studies report otherwise treating manic symptoms in hypothyroid state with thyroxine. We report a case of a patient whose acute mania appears to have been precipitated by thyroxine supplementation in hypothyroidism state. This case underscores the importance of thyroid screening in patients with mood and psychotic disorders, as well as the potency of thyroxine in producing manic symptoms.