Open AccessMolecular diagnosis of maturity onset diabetes of the young in India
Author(s) -
Veeir,
Aaron Chapla,
Nishanth Arulappan,
Thomas Nicolaï
Publication year - 2013
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.111636
Subject(s) - medicine , diabetes mellitus , maturity onset diabetes of the young , disease , obesity , population , type 2 diabetes , genetic testing , maturity (psychological) , pediatrics , environmental health , endocrinology , developmental psychology , psychology
Diabetes is highly prevalent in India and the proportion of younger patients developing diabetes is on the increase. Apart from the more universally known type 1 diabetes and obesity related type 2 diabetes, monogenic forms of diabetes are also suspected to be prevalent in many young diabetic patients. The identification of the genetic basis of the disease not only guides in therapeutic decision making, but also aids in genetic counselling and prognostication. Genetic testing may establish the occurrence and frequency of early diabetes in our population. This review attempts to explore the utilities and horizons of molecular genetics in the field of maturity onset diabetes of the young (MODY), which include the commoner forms of monogenic diabetes.