Open AccessEvaluation of diabetic polyneuropathy in Type 2 diabetes mellitus by nerve conduction study and association of severity of neuropathy with serum sFasL level
Author(s) -
Avijit Mondal,
Suvadeep Sen,
Debarati Chanda,
Sunanda Kundu,
Mitali Chatterjee,
Satinath Mukherjee
Publication year - 2012
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.104133
Subject(s) - medicine , peripheral neuropathy , diabetes mellitus , polyneuropathy , nerve conduction velocity , diabetic neuropathy , type 2 diabetes , type 2 diabetes mellitus , fas ligand , complication , logistic regression , gastroenterology , endocrinology , nerve conduction study , nerve conduction , apoptosis , biochemistry , chemistry , programmed cell death
Diabetes mellitus (DM), a growing health problem globally, has reached epidemic proportions in India. Recently, Fas-mediated apoptosis has been proposed as a causative factor responsible for neuronal degeneration in diabetic polyneuropathy (DPN), but there are very few studies to show association of serum soluble Fas ligand (sFasL) level with severity of neuropathy.