Open AccessWhat the future holds for gliptins
Author(s) -
Radhika Jindal,
Ayesha Ahmad,
Mahmudur Rahman Siddiqui,
Subhash Kumar Wangnoo
Publication year - 2012
Publication title -
indian journal of endocrinology and metabolism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.456
H-Index - 28
eISSN - 2230-9500
pISSN - 2230-8210
DOI - 10.4103/2230-8210.104050
Subject(s) - medicine , glycemic , pancreas , diabetes mellitus , pancreatic cancer , pancreatitis , endocrinology , cancer
Gliptins have revolutionised the treatment of Type 2 Diabetes Mellitus, addressing the hyperglycemia through its effects on the alpha and beta cells of the pancreas. In this article,we review the extra-glycemic effects of gliptins on central nervous system, cardiovascular biology and the bone health and concerns regarding pancreatitis and pancreatic cancer.