Open AccessEarly prenatal syphilis
Author(s) -
Santoshdev P Rathod,
Bela Shah
Publication year - 2010
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.73259
Subject(s) - medicine , syphilis , rapid plasma reagin , serology , pregnancy , penicillin , congenital syphilis , nose , dermatology , chest radiograph , surgery , antibody , radiography , immunology , antibiotics , treponema , human immunodeficiency virus (hiv) , biology , microbiology and biotechnology , genetics
Syphilis in pregnancy still remains a challenge despite the availability of adequate diagnostic tests for serological screening and penicillin therapy. We report a case of 2 month old female infant who presented with runny nose, papulosquamous lesions over both palms and soles and perianal erosions since 1 month after birth. Cutaneous examination revealed moist eroded areas in the perianal region and fine scaly lesions over palms and soles. Radiograph of both upper limbs and limbs revealed early periosteal changes in lower end of humerus and lower end of tibia. Diagnosis of early pre-natal syphilis was confirmed by Child's Serum Rapid Plasma Reagin Antibody test [S.RPR] being positive with 1:64 dilution while that of mother was 1:8.