Open AccessThe skin on the move but cold adapted: Fundamental misconceptions in the laboratory and clinic
Author(s) -
Terence J. Ryan
Publication year - 2010
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.73248
Subject(s) - medicine , neglect , epidermis (zoology) , factory (object oriented programming) , lymphatic system , histopathology , pathology , dermatology , anatomy , psychiatry , computer science , programming language
The skin is constantly on the move and at a temperature below 37ºC. The epidermis is a factory, and its blood supply and lymphatic drainage, as well as adipose tissue, are much dependent on movement and influenced by cooling. Neither histopathology (still pictures) nor in vitro studies at 37ºC reflect the true picture. Recent publications neglect older literature exploring these issues.