Open AccessTumor with the features of both squamous cell carcinoma and melanoma (melanocarcinoma)
Author(s) -
Elise Kochoumian,
Viktoryia Kazlouskaya,
Aaron R. Mangold,
Karan Lal,
Sandra Maia-Cohen,
Dirk M. Elston
Publication year - 2015
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.156422
Subject(s) - medicine , melanoma , basal cell , lentigo maligna , metastasis , pathology , cancer research , dermatology , cancer
Combined tumors of malignant melanoma (MM) and squamous cell carcinoma (SCC) are extremely rare and have unknown biological potential. Different theories of their development, including collision and dual/divergent differentiation, are proposed. Although some observations suggest an indolent course for such tumors, a case of MM metastasis was reported in a patient who initially presented with a combined MM-SCC tumor. Re-excisions of such tumors may show MM in situ and should be treated accordingly. Herein we present another case of a combined MM-SCC tumor in a 78 male patient with lentigo maligna seen after complete re-excision of the tumor.