Open AccessAssociation of anti-phospholipid antibodies with connective tissue diseases
Author(s) -
Reena Rai,
T Swetha
Publication year - 2015
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.153009
Subject(s) - serositis , medicine , connective tissue , mixed connective tissue disease , antibody , connective tissue disease , undifferentiated connective tissue disease , pathology , connective tissue disorder , systemic lupus erythematosus , proteinuria , anemia , immunology , disease , autoimmune disease , kidney
The antiphospholipid antibodies (APLA) are directed against phospholipids and their binding proteins and are frequently found in association with connective tissue disorders. Systemic lupus erythematoses (SLE) with APLA may cause a diagnostic dilemma as there are several manifestations like haemolytic anemia, thrombocytopenia, neurologic manifestations, leg ulcerations, serositis proteinuria which overlap in both these conditions. We conducted a study to find out the association of antiphospholipid antibodies with connective tissue diseases and compared the clinical and laboratory parameters between antiphoshpolipid antibody positive and antiphoshpolipid antibody negative group.