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Psoriasis is a chronic, immune-mediated skin disease with unknown etiology, with an epidermal turnover time of &lt;10 days compared to a normal turnover time of 4-8 weeks. This epidermal hyperproliferation accounts for many of the metabolic abnormalities including alteration in the serum levels of proteins and some trace elements.

indian dermatology online journal

Comparison of levels of serum copper, zinc, albumin, globulin and alkaline phosphatase in psoriatic patients and controls: A hospital based casecontrol study