
Localized bullous pemphigoid on sites of radiotherapy and lymphedema in the same patient
Author(s) -
Manikoth Payyanadan Binitha,
Veeravalli V. Vishnu,
Sreekanth Sukumarakurup,
Olassery Kalathingal Reena Mariyath
Publication year - 2014
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.146170
Subject(s) - medicine , bullous pemphigoid , lymphedema , dermatology , radiation therapy , surgery , cancer , antibody , immunology , breast cancer
Bullous pemphigoid (BP) is a blistering disorder due to autoantibodies to the epidermal basement membrane zone. The triggering factor could be localized damage to the skin by physical or chemical agents. We report a case of a 68-year-old woman with a three year history of oral lesions of BP following radiotherapy for carcinoma of the hypopharynx, and a three month history of BP over lymphedematous sites on the right hand and right lower limb. Localized BP induced by radiotherapy or lymphedema is rare; both factors working simultaneously in the same patient is even rarer.