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Aquagenic keratoderma. Two new case reports and a new hypothesis
Author(s) -
Georgi Tchernev,
Kristina Semkova,
José Carlos Cardoso,
Julian Ananiev,
Uwe Wollina
Publication year - 2014
Publication title -
indian dermatology online journal
Language(s) - English
Resource type - Journals
eISSN - 2249-5673
pISSN - 2229-5178
DOI - 10.4103/2229-5178.126025
Subject(s) - keratoderma , medicine , dermatology , palmoplantar keratoderma , young adult , hyperkeratosis , gerontology
Aquagenic keratoderma has been described as a transient condition affecting predominantly young females and defined clinically by the appearance of palmar hyper-wrinkling accentuated after immersion in water. We present two new cases with aquagenic palmoplantar acrokeratoderma - a child and a young male. A significant clinical improvement was achieved after topical treatment with aluminum salts. Aquagenic palmar keratoderma may be a clue to cystic fibrosis in adolescents and young adults. We developed a new hypothesis on its pathogenesis.

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