
Smoking-induced satellite associations in a rural population of south India: An in vitro study
Author(s) -
AN Uma,
Pajanivel Ranganadin,
Sonika Raj,
Lokeshmaran
Publication year - 2011
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.91148
Subject(s) - smoke , biomarker , cigarette smoke , medicine , tobacco smoke , population , environmental health , peripheral blood , carcinogen , dna damage , physiology , oncology , toxicology , biology , genetics , chemistry , dna , organic chemistry
Genotoxic carcinogens in cigarette smoke interact with DNA, causing cytotoxicity. Cytogenetic damage therefore seems to be an excellent biomarker for determining the effect of exposure to chromosome-damaging agents in cigarette smoke.