Open AccessAssociation study of methylenetetrahydrofolate reductase A1298C mutation with cerebral venous thrombosis risk in an Iranian population
Author(s) -
Habib Ghaznavi,
Soheili Zahra,
Samiei Shahram,
Mohammad Soleiman Soltanpour
Publication year - 2015
Publication title -
international journal of applied and basic medical research/international journal of applied and basic medical research
Language(s) - English
Resource type - Journals
eISSN - 2248-9606
pISSN - 2229-516X
DOI - 10.4103/2229-516x.165384
Subject(s) - methylenetetrahydrofolate reductase , genotyping , gastroenterology , medicine , homocysteine , venous thrombosis , genotype , hyperhomocysteinemia , risk factor , factor v , population , allele frequency , thrombosis , genetics , biology , gene , environmental health
Cerebral venous thrombosis (CVT) is an uncommon condition characterized by severe clinical manifestations and high mortality rate. There is limited data on the role of methylenetetrahydrofolate reductase (MTHFR) A1298C mutation as a risk factor for CVT development in Iranians.