Open AccessLymphatic filariasis: A view at pathological diversity
Author(s) -
Prashant Basavaraj Mahalingashetti,
Ramaswamy Anikode Subramanian,
Sushan Shweta Jayker,
Amrita Vijay
Publication year - 2014
Publication title -
tropical parasitology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.418
H-Index - 11
eISSN - 2229-7758
pISSN - 2229-5070
DOI - 10.4103/2229-5070.138544
Subject(s) - lymphatic filariasis , wolbachia , microfilaria , filariasis , lymphatic system , pathological , immune system , biology , pathology , immunology , medicine , helminths , host (biology) , ecology
Filariasis is traditionally diagnosed following screening of peripheral smear for microfilaria. Clinically lymphatic filariasis mimics the common local diseases. Thus, it is plausible to observe this parasitic infection in histological sections. We encountered three such cases, which displayed diverse patterns of immune response. Presence of both dead and viable worm at the same foci suggests that such immune response could be the result of parasitic death. Histological features such as endothelial injury and granulomatous response attests to the role of Wolbachia bacteria in influencing tissue response.