Open AccessStatus of Superoxide dismutase in transfusion dependent thalassaemia
Author(s) -
Lantip Rujito,
Sri Mulatsih,
Abdul Salam M. Sofro
Publication year - 2015
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4103/1947-2714.157480
Subject(s) - medicine , superoxide dismutase , ferritin , antioxidant , oxidative stress , chelation therapy , thalassemia , anemia , gastroenterology , biochemistry , chemistry
Thalassemia is a collection of genetic impairments in beta and alpha genes causing various states of anemia. Severe types of the disease need lifelong transfusions, leading to oxidant-antioxidant disturbance due to massive iron deposits.