Open AccessDual blockade of renin angiotensin system in reducing the early changes of diabetic retinopathy and nephropathy in a diabetic rat model
Author(s) -
Pugazhenthan Thangaraju,
Amitava Chakrabarti,
Dibyajyoti Banerjee,
Debasish Hota,
Tamilselvan,
Alka Bhatia,
Gupta Ak
Publication year - 2014
Publication title -
north american journal of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2250-1541
pISSN - 1947-2714
DOI - 10.4103/1947-2714.147978
Subject(s) - medicine , ramipril , telmisartan , diabetic retinopathy , diabetic nephropathy , nephropathy , diabetes mellitus , angiotensin ii receptor type 1 , olmesartan , endocrinology , retinopathy , angiotensin receptor , streptozotocin , ace inhibitor , kidney , linagliptin , pharmacology , angiotensin ii , angiotensin converting enzyme , type 2 diabetes , receptor , blood pressure
Diabetes mellitus is a real pandemic of the modern world and the incidence of the disease is increasing at a tremendous rate with a number of complications involving major systems of the human body. The renin angiotensin system (RAS) is considered to be involved in most of the pathological processes that result in diabetic nephropathy and retinopathy.