Open AccessMassive hemothorax following administration of intrapleural streptokinase
Author(s) -
Feng Yih Chai,
Yeh Chunn Kuan
Publication year - 2011
Publication title -
annals of thoracic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.639
H-Index - 33
eISSN - 1817-1737
pISSN - 1998-3557
DOI - 10.4103/1817-1737.82451
Subject(s) - medicine , hemothorax , streptokinase , coagulopathy , hemostasis , fibrinolysis , surgery , complication , hemorrhagic shock , chest tube , anesthesia , myocardial infarction , pneumothorax , cardiology , resuscitation
The administration of intrapleural streptokinase (IPSK) is widely practiced in the management of loculated empyema thoracis. To our knowledge, there have been only 4 cases of hemorrhagic complications attributed to the administration of IPSK reported in the literature. In this article, we report a case of a 17-year-old girl who received IPSK and developed shock, anemia, coagulopathy and massive hemothorax. Our discussion focuses on the hemorrhagic complication of chest tube insertion and the role of IPSK in blood clot lysis and inhibition of local hemostasis.