Open AccessGlioblastoma with signet ring cell morphology: A diagnostic challenge
Author(s) -
Naveen Krishnamoorthy,
Vidya Harini Veldore,
P.S. Sridhar,
MJ Govindrajan,
Shilpa Prabhudesai,
Digantha Hazarika,
BS Ajaikumar
Publication year - 2016
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 2248-9614
DOI - 10.4103/1793-5482.149998
Subject(s) - glioblastoma , pathology , signet ring cell , medicine , morphology (biology) , cell , cancer research , cancer , biology , adenocarcinoma , genetics
Glioblastoma (WHO Grade IV), the most frequent malignant brain tumor, can have varied morphologic variations like epithelial/glandular structures, granular cells, and lipidized cells. Glioblastoma with signet ring cell morphology is very unusual and can mimic a metastatic carcinoma. These rare tumors may be just a morphological variant or may signify a different carcinogenic pathway.