Open AccessThe impact of immunohistochemical markers of Ki-67 and p53 on the long-term outcome of growth hormone-secreting pituitary adenomas: A cohort study
Author(s) -
Maysam Alimohamadi,
Vahid Ownagh,
Leila Mahouzi,
Afshin Ostovar,
Kazem Abbassioun,
Abbas Amirjmshidi
Publication year - 2014
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 1793-5482
DOI - 10.4103/1793-5482.142732
Subject(s) - medicine , immunohistochemistry , cavernous sinus , prolactin , pituitary adenoma , ki 67 , hormone , cohort , magnetic resonance imaging , adenoma , gastroenterology , pathology , surgery , radiology
The tumoral biomarkers have a rather well known effect upon the tumor control period of several types of malignant lesions. The aim of this study was to evaluate the impact of immunohistochemical (IHC) markers of Ki-67 and p53 on the long-term outcome of growth hormone (GH)-secreting pituitary adenomas treated surgically.