Open AccessBetter Glasgow outcome score, cerebral perfusion pressure and focal brain oxygenation in severely traumatized brain following direct regional brain hypothermia therapy: A prospective randomized study
Author(s) -
Zamzuri Idris,
Mohd Sofan Zenian,
Muzaimi Mustapha,
Wan Zuraida Wan Abdul Hamid
Publication year - 2014
Publication title -
asian journal of neurosurgery
Language(s) - English
Resource type - Journals
ISSN - 1793-5482
DOI - 10.4103/1793-5482.142690
Subject(s) - medicine , hypothermia , cerebral perfusion pressure , oxygenation , anesthesia , glasgow outcome scale , cardiology , cerebral blood flow , glasgow coma scale
Induced hypothermia for treatment of traumatic brain injury is controversial. Since many pathways involved in the pathophysiology of secondary brain injury are temperature dependent, regional brain hypothermia is thought capable to mitigate those processes. The objectives of this study are to assess the therapeutic effects and complications of regional brain cooling in severe head injury with Glasgow coma scale (GCS) 6-7.