Open AccessAlantolactone and ZnO nanoparticles induce apoptosis activity of cisplatin in an ovarian cancer cell line (SKOV3)
Author(s) -
Shahriar Alipour,
Ghader Babaei,
ShivaGholizadeh-Ghaleh Aziz,
Somayeh Abolhasani
Publication year - 2022
Publication title -
research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.685
H-Index - 29
eISSN - 1735-9414
pISSN - 1735-5362
DOI - 10.4103/1735-5362.343083
Subject(s) - xiap , apoptosis , ovarian cancer , cisplatin , cancer research , chemistry , cyclin d1 , mtt assay , blot , cancer , microbiology and biotechnology , cell cycle , biology , medicine , programmed cell death , biochemistry , chemotherapy , gene , caspase
Ovarian cancer is one of the leading causes of cancer mortality in women. Despite the increase in cases of this cancer, the current therapeutic strategy is not effective. This study aimed to investigate the effect of cisplatin (Cis) with alantolactone (ALT) and ZnO nanoparticles (ZnONPs) in inducing apoptosis in SKOV3 ovarian cancer cells line.