Open AccessL-carnitine supplementation ameliorates insulin resistance in critically ill acute stroke patients: a randomized, double-blinded, placebo-controlled clinical trial
Author(s) -
M. Nejati,
Saeed Abbasi,
Shadi Farsaei,
Fatemeh Shafiee
Publication year - 2022
Publication title -
research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.685
H-Index - 29
eISSN - 1735-9414
pISSN - 1735-5362
DOI - 10.4103/1735-5362.329927
Subject(s) - medicine , placebo , insulin resistance , glycemic , homeostatic model assessment , sepsis , randomized controlled trial , intensive care unit , carnitine , stroke (engine) , population , insulin , mechanical ventilation , clinical trial , gastroenterology , alternative medicine , pathology , engineering , mechanical engineering , environmental health
Insulin resistance (IR) can negatively affect clinical outcomes in acute ischemic stroke (IS) patients. Safe and cost-saving interventions are still needed to improve glycemic indices in this population. The primary objective was to evaluate L-carnitine (LC) effects in acute IS patients' homeostatic model assessment of IR (HOMA-IR).