Open AccessEffects of Piper nigrum fruit and Cinnamum zeylanicum bark alcoholic extracts, alone and in combination, on scopolamine-induced memory impairment in mice
Author(s) -
Mohammad Teymuori,
Afsaneh Yegdaneh,
Mohammad Rabbani
Publication year - 2021
Publication title -
research in pharmaceutical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.685
H-Index - 29
eISSN - 1735-9414
pISSN - 1735-5362
DOI - 10.4103/1735-5362.323914
Subject(s) - cinnamomum zeylanicum , pharmacology , scopolamine , cholinergic , memory impairment , antioxidant , piper , aché , chemistry , memory improvement , traditional medicine , medicine , psychology , neuroscience , essential oil , biochemistry , acetylcholinesterase , cognition , food science , enzyme
Alzheimer's disease is a progressive brain disorder that is thought to be triggered via disruption of cholinergic neurons and enhanced oxidative stress. Therefore, antioxidant phytochemicals with the ability to fortify cholinergic function should help in preventing the progress of the disease. This study aimed at evaluating the combinational effects of two popular herbs one with anticholinesterase activity namely Piper nigrum and the other with antioxidant capacity, Cinnamomum zeylanicum .