Open AccessThe use of aminoguanidine, a selective inducible nitric oxide synthase inhibitor, to evaluate the role of nitric oxide on periapical healing
Author(s) -
Ali Reza Farhad,
Seyed Mohammad Javad Razavi,
Parnian Alavi Nejad
Publication year - 2011
Publication title -
dental research journal.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.334
H-Index - 17
eISSN - 2008-0255
pISSN - 1735-3327
DOI - 10.4103/1735-3327.86038
Subject(s) - nitric oxide synthase , nitric oxide , cats , dentistry , medicine , saline , root canal , maxillary canine
Nitric oxide (NO) is one of the many chemical mediators involved in inflammatory processes. In addition to periapical inflammation, NO can have a role in periapical healing. The purpose of this study was to evaluate the effect of aminoguanidine (AG) as a selective inhibitor of inducible nitric oxide synthase (iNOS) on the degree of healing response of periapical lesions of the canine teeth of cats.