Open AccessCorrelation of interleukin-6-174 GC and interleukin-6-572 GC gene polymorphisms with periodontal disease in an Iranian population
Author(s) -
Bahareh Nazemi Salman,
Surena Vahabi,
Alireza Biglari,
Simindokht Salavitabar,
Maryam Hassani Doabsari
Publication year - 2016
Publication title -
dental research journal.
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.334
H-Index - 17
eISSN - 2008-0255
pISSN - 1735-3327
DOI - 10.4103/1735-3327.187884
Subject(s) - correlation , periodontal disease , interleukin , disease , gene , interleukin 1β , medicine , population , genetics , biology , mathematics , environmental health , geometry , cytokine
Periodontal disease has a multifactorial etiology. A combination of microbial agents and environmental, habitual, systemic, and genetic risk factors is responsible for the development of periodontal disease. Host immune response causes the destruction of tooth-supporting structure and eventual tooth loss. This study aimed to assess the correlation of interleukin 6 (IL-6) -174-GC and IL-6-572-GC gene polymorphisms with periodontal disease in an Iranian population.