Open AccessClinical predictors of fulminant colitis in patients with Clostridium difficile infection
Author(s) -
Mohit Girotra,
Vivek Kumar,
Javaid M. Khan,
Pamela Damisse,
Rachel Abraham,
Vikas Aggarwal,
Sudhir K. Dutta
Publication year - 2012
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.93820
Subject(s) - medicine , clostridium difficile , diarrhea , leukocytosis , fulminant , univariate analysis , enterocolitis , colectomy , gastroenterology , clostridium difficile colitis , retrospective cohort study , logistic regression , surgery , multivariate analysis , antibiotics , disease , ulcerative colitis , microbiology and biotechnology , biology
Clostridium difficile infection (CDI) can affect up to 8% of hospitalized patients. Twenty-five percent CDI patients may develop C. difficile associated diarrhea (CDAD) and 1-3% may progress to fulminant C. difficile colitis (FCDC). Once developed, FCDC has higher rates of complications and mortality.