Open AccessInsulin resistance, steatosis, and fibrosis in Egyptian patients with chronic Hepatitis C virus infection
Author(s) -
Ahlam M Ahmed,
Marwa Hassan,
Alaa AbdElsayed,
Huwayda Hassan,
Ahmad Farooq Alsayed Hasanain,
Ahmed Helmy
Publication year - 2011
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.82578
Subject(s) - medicine , steatosis , insulin resistance , gastroenterology , liver biopsy , fibrosis , nonalcoholic fatty liver disease , hepatitis c virus , fatty liver , hepatitis c , biopsy , insulin , disease , immunology , virus
Both nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis C virus (HCV) infection are common in Egypt, and their coexistence is expected. There is controversy regarding the influence of NAFLD on chronic HCV disease progression. This study evaluates the effect of NAFLD on the severity of chronic hepatitis C (CHC) (necroinflammation and fibrosis) and assesses the relative contribution of insulin resistance syndrome to the occurrence of NAFLD in patients with chronic HCV infection.