Open AccessCorrelation of serology with morphological changes in gastric biopsy in Helicobacter pylori infection and evaluation of immunohistochemistry for H. pylori identification
Author(s) -
Shailaja Shukla,
Mukta Pujani,
Aditya Agarwal,
Mukta Pujani,
Anurag Rohtagi
Publication year - 2012
Publication title -
the saudi journal of gastroenterology/saudi journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.608
H-Index - 32
eISSN - 1998-4049
pISSN - 1319-3767
DOI - 10.4103/1319-3767.103428
Subject(s) - helicobacter pylori , serology , immunohistochemistry , rapid urease test , giemsa stain , gastritis , medicine , antibody , biopsy , pathology , gastric mucosa , staining , h&e stain , stomach , gastroenterology , immunology
Helicobacter pylori is implicated in various gastroduodenal diseases and many tests are available for its detection. The present study attempted to document the morphological changes in the gastric mucosa induced by H. pylori colonization and correlate them with the severity of the infection. The study also compared various diagnostic tests and evaluated the different staining methods used for H. pylori detection, especially immunohistochemical identification.