Open AccessAsymptomatic pontine and extra-pontine lesions in a patient with end-stage renal disease
Author(s) -
Rohitash Yadav,
Chandan Jyoti Das,
Soumita Bagchi,
Sanjay Kumar Agarwal
Publication year - 2016
Publication title -
saudi journal of kidney diseases and transplantation/našrat amraḍ wa zira'aẗ al-kulaẗ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.268
H-Index - 30
eISSN - 2320-3838
pISSN - 1319-2442
DOI - 10.4103/1319-2442.178578
Subject(s) - central pontine myelinolysis , medicine , asymptomatic , end stage renal disease , hemodialysis , stage (stratigraphy) , disease , transplantation , hyponatremia , paleontology , biology
Osmotic demyelination syndrome leading to central pontine/extra-pontine myelinolysis (CPM/EPM) occurs mainly in patients with history of alcohol abuse, malnourishment, following liver transplantation and less commonly, in association with other systemic diseases. Asymptomatic CPM/EPM is rare. Patients with end-stage renal disease (ESRD) who develop CPM/EPM are usually symptomatic with florid neurologic manifestations. Herein, we present a patient with ESRD on maintenance hemodialysis who was incidentally detected to have pontine and extra-pontine lesions suggestive of myelinolysis without any neurologic signs or symptoms.