Open AccessFrequency distribution of sickle cell anemia, sickle cell trait and sickle/beta-thalassemia among anemic patients in Saudi Arabia
Author(s) -
Mohieldin Elsayid,
Mohammed Jahman Al-Shehri,
Yasser Abdullah Alkulaibi,
Abdullah Alanazi,
Shoeb Qureshi
Publication year - 2015
Publication title -
journal of natural science, biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 30
eISSN - 2229-7707
pISSN - 0976-9668
DOI - 10.4103/0976-9668.166093
Subject(s) - medicine , sickle cell anemia , thalassemia , incidence (geometry) , hemoglobin electrophoresis , sickle cell trait , beta thalassemia , pediatrics , anemia , hemoglobin , disease , hemoglobinopathy , gastroenterology , fetal hemoglobin , pregnancy , genetics , biology , fetus , physics , optics
Notwithstanding, the growing incidence of sickle cell hemoglobinopathies (SCH) such as sickle cell anemia (SCA) or sickle cell disease, sickle/beta-thalassemia; the exact prevalence remains obscure in Saudi Arabia. Hence, this study is an attempt to determine the frequency of SCA and sickle cell trait (SCT) among all anemic patients with SCH treated at the King Abdul-Aziz Medical City (KAMC), Riyadh, Saudi Arabia. Furthermore, the hemoglobin (Hb) S and other Hb patterns (Hb AS and Hb F) were also estimated in SCA and SCT patients.