Open AccessPleomorphism of argyrophilic nucleolar organizer regions in oral submucous fibrosis and oral squamous cell carcinoma
Author(s) -
Komal Khot,
Keyuri J Kotak,
Kriti Bagri-Manjrekar,
Sheeba Alex,
Sheetal Choudhari
Publication year - 2015
Publication title -
journal of natural science, biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 30
eISSN - 2229-7707
pISSN - 0976-9668
DOI - 10.4103/0976-9668.166064
Subject(s) - pathology , pleomorphism (cytology) , oral submucous fibrosis , nucleolus organizer region , medicine , basal cell , oral mucosa , lesion , fibrosis , biology , immunohistochemistry , nucleolus , nucleus , psychiatry
Argyrophilic nucleolar organizer regions (AgNORs) is demonstrated to be useful in diagnostic pathology, mainly to distinguish benign lesions from their malignant counterparts. We aimed to correlate AgNORs pleomorphism with the severity of lesion in oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC) using a retrospective study on 45 archival tissues.