Open AccessIntronic SNPs of TP53 gene in chronic myeloid leukemia: Impact on drug response
Author(s) -
Sailaja Kagita,
V. Dayasagar Rao,
Satish Kumar Yadav,
Ravindranath Reddy,
D Surekha,
D. Nageswara Rao,
D. Raghunadharao,
Vishnupriya Satti
Publication year - 2012
Publication title -
journal of natural science, biology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.236
H-Index - 30
eISSN - 2229-7707
pISSN - 0976-9668
DOI - 10.4103/0976-9668.101910
Subject(s) - genetics , biology , myeloid leukemia , exon , intron , single nucleotide polymorphism , gene , mutation , microbiology and biotechnology , cancer research , genotype
TP53, located on chromosome 17p13, is one of the most mutated genes affecting many types of human cancers. Thus, we aimed at investigating the association of SNPs in TP53 gene with chronic myeloid leukemia (CML).