Open AccessSecondary metabolites of Cynodon dactylon as an antagonist to angiotensin II type1 receptor: Novel in silico drug targeting approach for diabetic retinopathy
Author(s) -
RK Jananie,
V. Priya,
K. Vijayalakshmi
Publication year - 2012
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.92497
Subject(s) - protein data bank (rcsb pdb) , cynodon dactylon , in silico , protein data bank , docking (animal) , chemistry , autodock , antagonist , binding site , active site , drug discovery , pharmacology , biochemistry , receptor , biology , medicine , protein structure , enzyme , veterinary medicine , botany , gene
To study the ability of the secondary metabolites of Cynodon dactylon to serve as an antagonist to angiotensin II type 1 receptor (AT(1)); activation of this receptor plays a vital role in diabetic retinopathy (DR).