Open AccessGanciclovir-tenofovir interaction leading to tenofovir-induced nephrotoxicity
Author(s) -
S. Radhika,
Shobha Jagdish Chandra Udutha,
M.V.S Subbalaxmi,
Y.S.N. Raju
Publication year - 2014
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.142452
Subject(s) - ganciclovir , tenofovir , foscarnet , human immunodeficiency virus (hiv) , nephrotoxicity , medicine , virology , cytomegalovirus , drug , enteritis , pharmacology , virus , human cytomegalovirus , viral disease , kidney , herpesviridae
Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)-infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofovir are the most commonly used drugs for the treatment of CMV and HIV infection, respectively, this case report showcases the potentiality of drug interaction as well as the safety measures to be taken when using these two drugs together in unavoidable situations.