Open AccessModulation of multidrug resistance 1 expression and function in retinoblastoma cells by curcumin
Author(s) -
Seethalakshmi Sreenivasan,
S. Ravichandran,
Umashankar Vetrivel,
Subramanian Krishnakumar
Publication year - 2013
Publication title -
journal of pharmacology and pharmacotherapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.301
H-Index - 34
eISSN - 0976-5018
pISSN - 0976-500X
DOI - 10.4103/0976-500x.110882
Subject(s) - curcumin , efflux , chemistry , binding site , western blot , p glycoprotein , docking (animal) , retinoblastoma , rhodamine 123 , in silico , microbiology and biotechnology , biochemistry , multiple drug resistance , pharmacology , biology , medicine , gene , nursing , antibiotics
To determine the possible interaction of curcumin with P-glycoprotein (P-gp) expression and function by in vitro and in silico studies.