Open AccessX-linked ichthyosis along with epidermolysis bullosa
Author(s) -
Shambulingappa Pallagatti,
Soheyl Sheikh,
Anupreet Kaur,
Amit Aggarwal,
Ravinder Singh
Publication year - 2012
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.95115
Subject(s) - ichthyosis , dermatology , epidermolysis bullosa , steroid sulfatase , lamellar ichthyosis , medicine , keratin , epidermis (zoology) , genetics , biology , pathology , anatomy , steroid , hormone
Ichthyoses are a heterogenous group of hereditary keratinization disorders that share in common the accumulation & shedding of large amounts of hyperkeratotic epidermis. Early reports of ichthyosis in the Indian and Chinese literature date back to several hundred years. X-linked recessive ichthyosis (XLI) is a common disorder of keratinization and affects males who inherit an X-chromosome having a steroid sulphatase genetic mutation. In the present communication we report a case of XLI and dystrophic epidermolysis bullosa in the same patient. To the best of our knowledge it has been reported only once before.