Open AccessEstimation of salivary tumor necrosis factor-alpha in chronic and aggressive periodontitis patients
Author(s) -
Sheeja Varghese,
Hima Thomas,
N. D. Jayakumar,
Sankari Malaiappan,
Reema Lakshmanan
Publication year - 2015
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.166816
Subject(s) - medicine , chronic periodontitis , aggressive periodontitis , periodontitis , periodontium , tumor necrosis factor alpha , clinical attachment loss , gastroenterology , dentistry
Periodontitis is a chronic bacterial infection characterized by persistent inflammation, connective tissue breakdown and alveolar bone destruction mediated by pro-inflammatory mediators. Tumor necrosis factor-alpha (TNF-α) is an important pro-inflammatory mediator that produced causes destruction of periodontal tissues.