Open AccessPrevalence of glutathione S-transferase M1 null polymorphism in tobacco users, oral leukoplakia and oral squamous cell carcinoma patients in South Indian population: A polymerase chain reaction study
Author(s) -
R. K. Tanwar,
Asha R Iyengar,
KS Nagesh,
Seema Patil,
BV Subhash
Publication year - 2015
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.152941
Subject(s) - medicine , leukoplakia , basal cell , chewing tobacco , oral leukoplakia , oral submucous fibrosis , population , polymerase chain reaction , gastroenterology , malignancy , pathology , cancer , genetics , biology , environmental health , gene
Tobacco abuse is a well-known risk factor for potentially malignant disorders as well as oral squamous cell carcinoma (SCC). Factors that influence tobacco-exposed individuals developing a malignancy may include a combination of total tobacco exposure and genetic susceptibility.