Open AccessDetermination of the antibacterial activity of simvastatin against periodontal pathogens, Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans: An in vitro study
Author(s) -
Shilpa Emani,
Gayathri V Gunjiganur,
Dhoom Singh Mehta
Publication year - 2014
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.137959
Subject(s) - porphyromonas gingivalis , aggregatibacter actinomycetemcomitans , simvastatin , antimicrobial , periodontitis , medicine , gingivitis , microbiology and biotechnology , minimum inhibitory concentration , context (archaeology) , pharmacology , dentistry , biology , paleontology
Statin treatment, apart from its hypolipidemic action has proven its antimicrobial activity by improving the survival rate of patients with severe systemic bacterial infections. Periodontitis is an inflammatory disorder of tooth supporting structures caused by a group of specific microorganisms. The objective of the present study was to determine the antimicrobial activity of pure simvastatin drug against the primary periodontal pathogens.