Open AccessCollision tumor of the palate: A rare case report
Author(s) -
Shoaib R Tippu,
Farzan Rahman,
Neha Sharma,
Shalabh Srivastava
Publication year - 2014
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.128682
Subject(s) - histogenesis , lesion , pathology , osteoma , medicine , glial fibrillary acidic protein , benign tumor , malignant peripheral nerve sheath tumor , anatomy , immunohistochemistry
This case report presents an unusual swelling of the palate in a 61-year-old-male patient. Histopathologically, it revealed features of two separate adjacent lesions, a spindle cells lesion showing diffuse immune-positivity for S-100 protein and focal positivity to glial fibrillary acid protein and an osseous lesion with numerous trabaculae of bone, adipocytes and myxoid tissue confirming the diagnosis of collision tumor of benign peripheral nerve sheath tumor and osteoma. Extensive search of English literature shows no reported cases of peripheral nerve sheath tumor with osteoma. The probable histogenesis of this collision tumor is discussed in detail. The purpose of this case report is to document this rare case in the literature so as to increase the awareness of this entity.