Open AccessProtein carbonyl: An oxidative stress marker in gingival crevicular fluid in healthy, gingivitis, and chronic periodontitis subjects
Author(s) -
A.R. Pradeep,
MV Ramchandraprasad,
Pavan Bajaj,
Nishanth S. Rao,
Esha Agarwal
Publication year - 2013
Publication title -
contemporary clinical dentistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.289
H-Index - 21
eISSN - 0976-237X
pISSN - 0976-2361
DOI - 10.4103/0976-237x.111589
Subject(s) - gingivitis , periodontitis , chronic periodontitis , medicine , oxidative stress , biomarker , dentistry , gastroenterology , reactive oxygen species , biology , biochemistry
A defined role for reactive oxygen species (ROS) in the tissue destruction that characterizes periodontitis has been described. Protein carbonyl (PC) is the most widely used biomarker for oxidative damage to proteins, and reflects cellular damage induced by multiple forms of ROS. The purpose of this study is to determine the presence of PC in gingival crevicular fluid (GCF) in healthy, gingivitis, and chronic periodontitis (CP) subjects and to find an association, if any.