Open AccessAmelogenin in odontogenic cysts and tumors: An immunohistochemical study
Author(s) -
Praveen Anigol,
Venkatesh V Kamath,
Krishnanand Satelur,
Nagaraja Anand,
Komali Yerlagudda
Publication year - 2014
Publication title -
national journal of maxillofacial surgery
Language(s) - English
Resource type - Journals
eISSN - 2229-3418
pISSN - 0975-5950
DOI - 10.4103/0975-5950.154822
Subject(s) - amelogenin , immunohistochemistry , pathology , odontogenic , enamel paint , carcinogenesis , odontogenic tumor , medicine , biology , gene , dentistry , genetics
Amelogenins are the major enamel proteins that play a major role in the biomineralization and structural organization of enamel. Aberrations of enamel-related proteins are thought to be involved in oncogenesis of odontogenic epithelium. The expression of amelogenin is possibly an indicator of differentiation of epithelial cells in the odontogenic lesions.