Open AccessThe Influence of pluronic F68 and F127 nanocarrier on physicochemical properties, in vitro release, and antiproliferative activity of thymoquinone drug
Author(s) -
Salwa Shaarani,
Shahrul Bariyah Sahul Hamid,
Noor Haida Mohd Kaus
Publication year - 2017
Publication title -
pharmacognosy research
Language(s) - English
Resource type - Journals
eISSN - 0976-4836
pISSN - 0974-8490
DOI - 10.4103/0974-8490.199774
Subject(s) - thymoquinone , micelle , dynamic light scattering , poloxamer , nanocarriers , chemistry , bioavailability , drug delivery , particle size , polymer , nuclear chemistry , solubility , materials science , chemical engineering , aqueous solution , organic chemistry , nanoparticle , nanotechnology , copolymer , antioxidant , pharmacology , medicine , engineering
This study reports on hydrophobic drug thymoquinone (TQ), an active compound found in the volatile oil of Nigella sativa that exhibits anticancer activities. Nanoformulation of this drug could potentially increase its bioavailability to specific target cells.